Korean Circ J.  2000 Mar;30(3):365-368. 10.4070/kcj.2000.30.3.365.

A Case of Myocardial Injury after Phenylpropanolamine Ingestion

• Yoon WC
• Yeo DG
• Kim HJ
• Park JK
• Doh JH
• Ryu JK
• Choi JY
• Chang SG

• KMID: 2145673
• DOI: http://doi.org/10.4070/kcj.2000.30.3.365

Abstract

Phenylpropanolamine is a sympathomimetic amine used widely as a decongestant or appetite suppressant. Reports of the myocardial injury from the use of phenylpropanolamine are rare and the mechanism of the myocardial injury is not known clearly. We experienced a case of myocardial injury after ingestion of phenyl-propanolamine. A 46-year-old woman was admitted because of chest pain and dyspnea after ingestion of 5 tablets of anorectic pill containing phenylpropanolamine 75 mg per tablet. The serum creatine kinase MB isoenzyme levels were elevated and electrocardiographic abnormalities suggesting myocardial infarction were seen in the precordial lead. In echocardiograpy, left ventricular anteroseptal wall motion was nearly akinetic but coronary angiography showed normal coronary arteries except sluggish blood flow in left anterior descending artery.

Keyword

Phenylpropanolamine; Myocardial injury

MeSH Terms

Appetite
Arteries
Chest Pain
Coronary Angiography
Coronary Vessels
Creatine Kinase
Dyspnea
Eating*
Electrocardiography
Female
Humans
Middle Aged
Myocardial Infarction
Phenylpropanolamine*
Tablets
Creatine Kinase
Phenylpropanolamine
Tablets