Korean Circ J.  2003 Sep;33(9):827-831. 10.4070/kcj.2003.33.9.827.

A Case of Recurrent In-Stent Restenosis with Abundant Proteoglycan Component

Affiliations
  • 1The Heart Center of Chonnam National University Hospital, Gwangju, Korea. myungho@chollian.net
  • 2Chonnam National University Research Institute of Medical Sciences, Gwangju, Korea.

Abstract

A percutaneous coronary intervention (PCI) is known to be one of effective methods in the treatment of coronary artery disease. However, restenosis remains a major limitation to a PCI. Although neointimal cell proliferation is suspected to be the major cause of coronary stent restenosis, few histological characterizations of recurrent instent restenosis exist. We report a case of a 61-year-old man suffering from unstable angina due to secondary coronary in-stent restenosis in the proximal left anterior descending artery (LAD). An atherectomized tissue, obtained by a directional coronary atherectomy, showed myxoid tissue, characterized by a few stellate smooth muscle cells in the abundant extracellular matrix, which was blue-colored proteoglycan on modified Movat staining.

Keyword

Stents; Restenosis; Cells

MeSH Terms

Angina, Unstable
Arteries
Atherectomy, Coronary
Cell Proliferation
Coronary Artery Disease
Extracellular Matrix
Humans
Middle Aged
Myocytes, Smooth Muscle
Percutaneous Coronary Intervention
Proteoglycans*
Stents
Proteoglycans
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