Evaluation of the MAS Quality Control Materials for Chemistry and Urinalysis

Shin, Sue; Yoon, Jong Hyun

Abstract

BACKGROUND: To evaluate the stability and the precision of quality control materials for clinical chemistry analytes, we compared liquid quality control materials, Moni-Trol H (MAS Inc., Camarillo, CA, USA) with lyophilized and other liquid quality control materials. For urinalysis, liquid MAS UA Controls were compared with analyte affixed-strip type quality control materials.
METHODS
Using Hitachi-7600 (Hitachi, Tokyo, Japan), we analyzed lyophilized Seronorm & Pathonorm (SERO AS, Billingstad, Norway) and Moni-Trol H for 26 commonly measured chemistry analytes for 3~4 weeks. Using Synchron CX-7 (Beckman Coulter Inc., Fullerton, CA, USA), liquid Decision (Beckman Coulter) and Moni-Trol H were compared for 12 emergency chemistry analytes. For urinalysis, MAS UA Controls were compared with Chek-Stix (Bayer, Elkhart, IN, USA). We evaluate the stability of analyte by regression coefficient and the imprecision by coefficient of variation.
RESULTS
Moni-Trol H was more stable than Seronorm & Pathonorm and Decision. The imprecision was more evident with Moni-Trol H than the others, but the CVs of Moni-Trol H were within 10%. In urinalysis, all the results were within two semi-quantity levels with both MAS UA Control and Chek-Stix.
CONCLUSIONS
The MAS quality control materials for common chemistry analytes and urinalysis showed good stability and comparable precision. The materials were efficient for laboratory use due to the advantage of human source based liquid form and long-term stability after preparation.