J Korean Surg Soc.  2001 Oct;61(4):450-454.

Retroperitoneal Castleman's Disease with Pure Red Cell Aplasia

• Chang SH
• Doh JT
• Park DJ
• Chang MC
• Noh DY
• Youn YK
• Oh SK

Abstract

Castleman's disease is a distinct lymphoproliferative disorder of unknown origin, which creates both a diagnostic and therapeutic dilemma for most physicians. Here, we present a case of hyaline-vascular and solitary Castleman's disease associated with pure red cell aplasia. A 49-year old woman was admitted suffering from severe anemia. A bone marrow biopsy showed marked erythroid hypoplasia. A solitary retroperitoneal mass was excised and proven to be Castleman's disease with hyaline-vascular type histology. Removal of the mass led to a rapid reversal of anemia. No evidence of recurrence was found 1 year after the excision.

Keyword

Castleman's disease; Hyaline-vascular; Solitary

MeSH Terms

Anemia
Biopsy
Bone Marrow
Female
Giant Lymph Node Hyperplasia*
Humans
Lymphoproliferative Disorders
Middle Aged
Recurrence
Red-Cell Aplasia, Pure*