Korean J Med.
2007 Sep;73(3):336-341.
A case of Wegener's granulomatosis complicated by non-small cell lung cancer
- Affiliations
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- 1Department of Internal Medicine, College of Medicine, Kangwon National University, Chuncheon, Korea. sysong@kangwon.ac.kr
- 2Department of Pathology, College of Medicine, Kangwon National University, Chuncheon, Korea.
Abstract
- Vasculitis may be a manifestation of the paraneoplastic syndrome in association with solid and hematological cancers. There are few reports of paraneoplastic antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis in patients with solid tumors. Wegener's granulomatosis is a systemic vasculitis characterized by necrotizing granulomatous vasculitis of the upper and lower respiratory tracts together with glomerulonephritis and are ANCA-positive. We experienced a case of Wegener's granulomatosis complicated by non-small cell lung carcinoma (NSCLC) and we report this case with a brief review of the literature.
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