Korean J Occup Environ Med.
2011 Jun;23(2):183-191.
Association Between Blood Lead Concentration and Computerized Neurobehavioral Performance in Korean Elementary School Students
- Affiliations
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- 1Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Department of Preventive Medicine and Public Health, College of Medicine, Yeungnam University, Korea. jsakong@med.yu.ac.kr
- 2Department of Preventive Medicine, College of Medicine, Seoul National University, Korea.
- 3Department of Preventive Medicine, College of Medicine, Chosun University, Korea.
- 4Department of Preventive Medicine, College of Medicine, Dankook University, Korea.
Abstract
OBJECTIVES
This study was conducted to evaluate association between computerized neurobehavioral performance and blood lead concentration in Korean elementary school students.
METHODS
The subjects were 1,077 elementary school students of Seoul, Busan, Daegu and Gwangju. Blood lead concentration was measured and computerized neurobehavioral performance tests were performed.
RESULTS
Blood lead concentration of the subjects was in the range of 0.20 and 7.39 microg/dl. The geometric mean of the subjects' blood lead concentration was 1.41 microg/dl. As blood lead concentration increased, reaction time to the symbol digit tended to increase significantly and linearly. As a result of LOWESS(locally weighted scatterplot smoothing), increasing reaction time to the symbol digit was observed.
CONCLUSIONS
As blood lead concentration under the CDC (center for disease control and prevention) reference value increased, reaction time to the symbol digit tended to increase. But, as the number of subjects over 3 microg/dl is small, it is difficult to make a definite conclusion. If confounding variables are controlled properly in a follow-up study, we can obtain a more definite conclusion.
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