Korean J Urol.  2007 Oct;48(10):1088-1091. 10.4111/kju.2007.48.10.1088.

Metastatic Renal Cell Carcinoma to the Urinary Bladder after Radical Nephrectomy

• Kim JH
• Myung SC

• KMID: 2139744
• DOI: http://doi.org/10.4111/kju.2007.48.10.1088

Abstract

We report a case of metastatic renal cell carcinoma to the urinary bladder. A 61-year-old man presented with gross hematuria. The patient had been treated with a radical nephrectomy at 59 years of age, for renal cell carcinoma. Cystoscopy revealed two polyploid tumors protruding into to the urinary bladder. A transurethral resection was performed and the pathological diagnosis of the lesion in the urinary bladder was a renal cell carcinoma. Metastases to the paratracheal lymph nodes were confirmed on the chest computed tomography. The patient was treated with immunotherapy(5-fluorouracil, interferon-a, interleukin-2) for 20 weeks. Eleven months later, the patient is alive and well.

Keyword

Renal cell carcinoma; Urinary bladder; Metastasis

MeSH Terms

Carcinoma, Renal Cell*
Cystoscopy
Diagnosis
Hematuria
Humans
Lymph Nodes
Middle Aged
Neoplasm Metastasis
Nephrectomy*
Polyploidy
Thorax
Urinary Bladder*

Figure

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  Fig. 1 Abdominal computed tomography shows ill-defined large heterogenic enhanced mass with necrotic changes in the left kidney.

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  Fig. 2 (A) Primary renal cell carcinoma composed of clear cells. Hematoxylin-Eosin stain, ×400. (B) Renal cell carcinoma metastatic to the urinary bladder. Hematoxylin-Eosin stain. Tumor showing clear cell pattern identical histologically to previous renal cell carcinoma, ×400.

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  Fig. 3 (A) Cystoscopic appearance of two metastatic lesions, 1.5cm in size, on the posterior wall of the urinary bladder. (B) CT scan with intravenous contrast demonstrates a well enhanced mass 1.5cm in size, at the posterior wall.

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  Fig. 4 Single well-enhancing mass (3.4×2.6cm) at the right paratracheal region of the upper mediastinum (A) and disappearance of the metastatic lymph node in right upper mediastinal area (B).

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