Nucl Med Mol Imaging.  2014 Mar;48(1):72-74.

Impact of Nonosseous Findings on 18F-NaF PET/CT in a Patient with Ductal Breast Carcinoma

• Kuyumcu S
• Adalet I
• Isik EG
• Unal SN

Abstract

18F-NaF was used as a bone-seeking PET tracer for skeletal imaging until the introduction of the widely available 99mTc-labeled bone agents. However, there is renewed clinical interest in 18F-NaF since prior technical and logistic limitations to its routine use are no longer present, and, as a consequence, it is likely that uptake unrelated to bone and nonosseous findings will be encountered more frequently. As a result of tumoral necrosis, soft tissue metastases may demonstrate 18F-NaF avidity due to dystrophic calcification. On the other hand, all non-osseous findings, whether 18F-NaF avid or not, may provide important diagnostic information that may alter the course of the disease, including treatment options. Herein we present a patient with ductal carcinoma of the breast in whom findings unrelated to the skeletal system in 18F-NaF PET/CT altered the treatment strategy.

Keyword

18F-NaF PET/CT; 18F-FDGPET/CT; Bone metastasis; Breast carcinoma

MeSH Terms

Breast
Breast Neoplasms*
Carcinoma, Ductal
Hand
Humans
Necrosis
Neoplasm Metastasis
Positron-Emission Tomography and Computed Tomography*