Yeungnam Univ J Med.  2012 Jun;29(1):58-60. 10.12701/yujm.2012.29.1.58.

A Case of Scopolamine-Induced Central Anticholinergic Syndrome

• Shin DS
• Lee HS
• Lee SJ

• KMID: 2138661
• DOI: http://doi.org/10.12701/yujm.2012.29.1.58

Abstract

Central anticholinergic syndrome occurs when an anticholinergic substance works in vivo or as a result of the insufficient release of acetylcholine. Its symptoms include confusion, agitation, behavioral change, hallucination, blurred vision, and dysarthria. Occasionally, these symptoms occur with the use of a scopolamine patch. A 54-year-old female complained of behavioral change and confused mentality. She attached a scopolamine patch at the postauricular area in the morning of the day before her hospital visit. Neurological examination revealed bilateral symmetric mydriasis without light reflex. The brain MRI was normal, and electroencephalography showed nonspecific abnormalities. The patient recovered completely after the removal of the scopolamine patch.

Keyword

Central anticholinergic syndrome; Scopolamine patch

MeSH Terms

Acetylcholine
Brain
Dihydroergotamine
Dysarthria
Electroencephalography
Female
Hallucinations
Humans
Light
Middle Aged
Mydriasis
Neurologic Examination
Reflex
Scopolamine Hydrobromide
Vision, Ocular
Acetylcholine
Dihydroergotamine
Scopolamine Hydrobromide