J Korean Neurol Assoc.
1993 Jun;11(2):229-234.
Two Cases of Suspected Typhoid Encephalitis Treated with High Dose Dexamethasone
- Affiliations
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- 1Department of Neurology, College of Medicine, Ulsan University, Asan Medical Center, Korea.
- 2Department of Internal Medicine, College of Medicine, Ulsan University, Asan Medical Center, Korea.
Abstract
- Typhoid fever is one of the important contagious diseases. Typhoid fever of severe category is defined as the condition in which a febrile patient shows shocks or an altered state of consciousness ranging from delirium to coma. High dose dexarnethasone therapy is considered very effective in these life-threatening conditions. We report two severe hrphoid fever cases, which were treated with high dose dexarnethasone (dexamethasone 3mg/kg IV and lmg/kg q6hrs for 48 hrs) with a great success and we believe that one of the two cases is the first Korean case in the literature who had cerebellar ataxia and cortical tremor as a manifestation of the CNS involvement of typhoid fever.
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