J Clin Neurol.  2007 Sep;3(3):150-153. 10.3988/jcn.2007.3.3.150.

Focal Hand Dystonia Secondary to Basal Ganglia Germinoma

Affiliations
  • 1Department of Neurology, The Catholic University of Korea, Seoul, Korea. ks1007@catholic.ac.kr
  • 2Department of Radiology, The Catholic University of Korea, Seoul, Korea.

Abstract

Descriptions of symptomatic focal dystonia caused by focal lesions of the central nervous system (CNS) are rare in the literature. We report a 9-year-old child who experienced sudden-onset left-hand dystonia for 6 months. Brain magnetic resonance imaging showed a mass lesion involving the putamen, globus pallidus, head of caudate, and the anterior limb of the internal capsule. Histopathological and immunocytochemical examinations of the mass revealed features characteristic of malignant germinoma. CNS germinoma in the basal ganglia is very rare. Combining previous reports in the literature with the anatomical and clinical presentation of our case suggests that this phenomenon results from disruption of the pathways within and adjacent to the basal ganglia.

Keyword

Basal ganglia; Germinoma; Focal dystonia
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