Hanyang Med Rev.
2005 Nov;25(4):22-31.
Risk Factors of Chronic Obstructive Pulmonary Disease (COPD)
- Affiliations
-
- 1Department of Internal Medicine, College of Medicine, Pusan National University, Korea. snkpark@pusan.ac.kr
Abstract
- Defining risk factors obviously is important in establishing strategies for prevention and treatment of chronic obstructive pulmonary disease(COPD). Much evidence concerning risk factors for COPD comes from cross-sectional and longitudinal studies that identify causal associations rather than cause-effect relationship, and therefore, current understanding of risk factors for COPD is incomplete, yet. However, identification of cigarette smoking is the most important risk factor revealed to be a cause and leads to smoking cessation programs, which are key ingredients of COPD prevention. Influences of gender, genes other than alpha1-antitrypsin deficiency, airway hyperresponsiveness, occupational dusts, fumes, chemicals, childhood pulmonary infection and socioeconomic status to the development of COPD have been suggested as possible risk factors.