Electrolyte Blood Press.  2007 Jun;5(1):47-49. 10.5049/EBP.2007.5.1.47.

SIADH Associated with Prostate Cancer

• Lee KS
• Kang TW
• Ma SK
• Kim SW
• Kim NH
• Choi KC

• KMID: 2134805
• DOI: http://doi.org/10.5049/EBP.2007.5.1.47

Abstract

Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is the most common disease leading to hyponatremia, and it is characterized by an inappropriately elevated serum ADH level relative to serum osmolality. This syndrome may occur in a variety of clinical settings including malignancies. However, it is rarely observed in association with prostate cancer. Moreover, its pathogenesis and clinical characteristics have not been completely understood. We report a case of SIADH associated with prostate cancer in a 64-year-old male patient with a literature review.

MeSH Terms

Humans
Hyponatremia
Inappropriate ADH Syndrome*
Male
Middle Aged
Osmolar Concentration
Prostate*
Prostatic Neoplasms*

Figure

• 

  Fig. 1 Pathologic finding of prostate biopsy. Prostatic tissue shows poorly differentiated adenocarcinoma (H&E,×400).

• 

  Fig. 2 The clinical course of the patient.

Reference

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