Clin Exp Otorhinolaryngol.  2012 Sep;5(3):173-176. 10.3342/ceo.2012.5.3.173.

Nasal Hemangiopericytoma Causing Oncogenic Osteomalacia

Affiliations
  • 1Department of Otorhinolaryngology, Chosun University College of Medicine, Gwangju, Korea. happyent@naver.com

Abstract

Oncogenic osteomalacia is a rare cause that makes abnormalities of bone metabolism. Our case arose in a 47-year-old woman presenting a nasal mass associated with osteomalacia. We excised the mass carefully. After surgery, it was diagnosed as hemangiopericytoma and her symptoms related with osteomalacia were relieved and biochemical abnormalities were restored to normal range. We report and review a rare case of nasal hemangiopericytoma that caused osteomalacia.

Keyword

Nasal hemangiopericytoma; Osteomalacia

MeSH Terms

Female
Hemangiopericytoma
Humans
Middle Aged
Neoplasms, Connective Tissue
Osteomalacia
Reference Values
Neoplasms, Connective Tissue

Figure

  • Fig. 1 Endoscopic finding showed a smooth pinkish hard mass filling the left nasal cavity.

  • Fig. 2 Preoperative contrast-enhanced coronal (A) and axial (B) computed tomography scan revealed a expansile hypervascular tumor in the left nasal cavity and post ethmoid sinus that demonstrated a scattered calcification and expansive bony destruction.

  • Fig. 3 (A) Histologic findings of the tumor. Microscopically, this tumor is composed of mainly spindle cells, abundunt blood vessels and metaplastic bony tissues. Spindle cells are interspersed between blood vessels. (B) In immunohistochemical studies, endothelial cells of blood vessels have immunoreactivity for CD34.


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