Nucl Med Mol Imaging.  2015 Dec;49(4):325-328. 10.1007/s13139-015-0360-2.

Malignant Peritoneal Mesothelioma Masquerades as Peritoneal Metastasis on 18F-FDG PET/CT Scans; a Rare Diagnosis that Should Not Be Missed

• Claimon A
• Bang JI
• Cheon GJ
• Kim EE
• Lee DS

• KMID: 2132240
• DOI: http://doi.org/10.1007/s13139-015-0360-2

Abstract

Malignant peritoneal mesothelioma (MPM) is a rare but fatal tumor. The clinical presentations and imaging findings are nonspecific and resemble various diseases, including peritoneal metastasis. Imaging findings of MPH on 18F-18F-fluorodeoxyglucose (18F-FDG) positron emission tomography (PET)/computed tomography (CT) are diverse and not well described. We report the two cases of biopsy-proven MPH using 18F-FDG PET/CT. In our cases, interesting disease patterns-including MPH arising from visceral peritoneal lining of kidney that suffer from polycystic disease and from the parietal peritoneum beneath the appendectomy scar-were presented. One case showed classical metastases localized within the abdominal cavity; while the other case exhibited the rare pattern of extensive multi-organ metastases. By knowing the possible variations and diagnostic pitfalls of 18F-FDG PET/CT findings in MPM, more accurate interpretation of such mysterious cancer is attainable.

Keyword

Mesothelioma; Peritoneum; F-18 fluorodeoxyglucose; Positron emission tomography

MeSH Terms

Abdominal Cavity
Appendectomy
Diagnosis*
Fluorodeoxyglucose F18*
Kidney
Mesothelioma*
Neoplasm Metastasis*
Peritoneum
Positron-Emission Tomography
Positron-Emission Tomography and Computed Tomography*
Fluorodeoxyglucose F18