J Gynecol Oncol.  2008 Jun;19(2):150-153. 10.3802/jgo.2008.19.2.150.

A case of primary retroperitoneal undifferentiated endometrial stromal sarcoma after concurrent chemoradiation therapy for cervical cancer

• Kang WD
• Kim CH
• Cho MK
• Kim JW
• Kim YH
• Choi HS
• Kim SM

• KMID: 2129917
• DOI: http://doi.org/10.3802/jgo.2008.19.2.150

Abstract

Endometrial stromal sarcoma (ESS) is a relatively rare uterine sarcoma, especially extrauterine ESS. Furthermore, retroperitoneal ESS are extremely rare. Up to now, there are only four cases of primary retroperitoneal ESS reported in the literature. We report one case of primary retroperitoneal undifferentiated endometrial stromal sarcoma after concurrent chemoradiation therapy for cervical cancer with a brief review of the literature.

Keyword

Sarcoma; Endometrial stromal; Retroperitoneal space; Uterine cervical neoplasms

MeSH Terms

Retroperitoneal Space
Sarcoma
Sarcoma, Endometrial Stromal
Uterine Cervical Neoplasms

Figure

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  Fig. 1 Pelvic MRI showing a normal uterus (A), and about a 7.5×6.2×5.8 cm retroperitoneal irregular shaped heterogenous enhancing mass that encased the left external iliac vessels (B, C, D). (A) Sagittal T2 weighted image, (B) Axial T1 weighted image, (C) Axial T2 weighted image, (D) Axial gadolinium enhanced T1 weighted image. The arrow points to the left external iliac vessel.

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  Fig. 2 Histological and immunohistochemical findings. Low magnification shows solid proliferation of oval to spindlecells (A, hematoxylin-eosin, ×40). The tumor cells show nuclear pleomorphism and increased mitotic activity (B, hematoxylin-eosin, ×200). Immunohistochemically, the tumor cells were immunoreactive to vimentin (C, ×200) and CD 10 (D, ×200).

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