Intravitreal Injection of Triamcinolone Acetonide in Vitrectomy with Silicone Oil Placement

Byon, Ik Soo; Lee, Ji Eun; Oum, Boo Sup

Abstract

PURPOSE: To evaluate safety and efficacy of intravitreal triamcinolone acetonide (TA) injection at the end of pars plana vitrectomy with silicone oil tamponade.
METHODS
Eyes which underwent pars plana vitrectomy with silicone oil placement were enrolled. They were followed up for at least 6 months. Group I (twenty-three consecutive eyes) received an intravitreal injection of 4 mg TA at the end of the surgery, whereas Group II (twenty-six eyes) did not.
RESULTS
Postoperative vision improved by 2 lines or more in 9 eyes (39.1%) of Group I and 9 eyes (34.6%) of Group II. The posterior pole was attached in all of Group I (100.0%) and twenty-four eyes (92.3%) of Group II (P=0.17). The postoperative BCVA was 5/200 or better in fifteen eyes (65.2%) of Group I and fourteen eyes (53.8%) of Group II (P=0.51). Eight eyes (34.8%) in Group I and six eyes (23.1%) in Group II had an intraocular pressure higher than 21 mmHg (P=0.36). All of them were controlled with medications. Two eyes in Group II required an additional operation due to recurrence of tractional retinal detachment from the fibrous membrane. Visually significant ocular complications related with TA injections were not noted.
CONCLUSIONS
The intravitreal injection of TA into silicone-filled vitrectomized eyes seems safe and efficient. But, a prospective study is necessary to demonstrate the long-term safety and efficacy.