J Korean Ophthalmol Soc.
2002 Nov;43(11):2234-2240.
The Pro g ression of Myopia Associated with Retinopathy of Prematurity
- Affiliations
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- 1Department of Ophthalmology, College of Medicine, Soonchunhyang University, Korea. eyedrlim@hanmail.net
Abstract
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PURPOSE: To discover the characteristics and rates of myopic progression with increasing age in children who have had history of retinopathy of prematurity (ROP).
METHODS
Retrospective chart review was performed of 72 eyes in 36 children who were diagnosed with ROP. Inclusion criteria were myopia over -0.5 diopter and the children that could have been followed for at least 5 years or longer. The subjects with stage 4 or 5 ROP were excluded. Data on the retinoscopic refractions at every 6 month in each patient were recorded. We measured the annual rates of myopic progression in each subgroup which were divided according to the severity of ROP, treatment modality, and the different age intervals.
RESULTS
Overall annual rates of myopic progression was -0.53 D/year. The severity of ROP was not correlated with the degree of myopia and the rates of myopic progression. In terms of the rates of myopic progression, statistical significance was found only in subgroups who were treated by cryotherapy. The myopia in age group over 5 years showed less progression than that in age group under 5 years. In the patients with anisometropia, there was a tendency that the discrepancy in the refractions of both eyes decreased gradually with increasing age although there was no statistical significance.
CONCLUSIONS
The rate of myopic progression was not directly correlated with the severity of ROP. But the myopia in patients who had undergone cryotherapy showed a marked progression with significantly higher rate.
