J Korean Ophthalmol Soc.  2002 Nov;43(11):2136-3143.

Efficacy of Intracameral Lidocaine During Phacoemulsification in Vitrectomized Eye

Affiliations
  • 1Department of Ophthalmology, Busan Paik Hospital, InJe University Medical college, Korea. hereye@ijnc.ijne.ac.kr

Abstract

PURPOSE: This study was designed to evaluate the efficacy of intracameral lidocaine injection on patient' s pain relief during phacoemulsification in vitrectomized eyes and the influence on the corneal endothelial cells.
METHODS
A prospective, double blind clinical trial was performed on 60 eyes of 60 patients who had undergone phacoemulsification from October 2000 to February 2001 at Busan PAIK Hospital. Thirty eyes had prior vitrectomy. Before surgery specular microscopic examination was performed. The patients were divided into vitrectomized and nonvitrectomized groups, and the lidocaine or placebo (BSS) was injected into the anterior chamber of 15 eyes each in two subgroups within each group. Pain was assessed using a visual analogue scale before, during and after operation. Endothelial cells were examinined at one week, one month, and three months after operation with a specular microscope.
RESULTS
In vitrectomized patients, intracameral lidocaine injection resulted in significantly lower intraoperative pain score. There were no significant differences in morphological changes of endothelium between lidocaine and placebo groups.
CONCLUSIONS
Intracameral lidocaine injection with topical anesthesia had significant effect in intraoperative pain relief during phacoemulsification in vitrectomized eyes. There was no significant effects on corneal endothelium. We conclude that intracameral anesthesia is safe and reduces intraoperative pain in vitrectomized eyes.

Keyword

Cataract; Corneal endothelial cell; Intracameral lidocaine; Phacoemulsification

MeSH Terms

Anesthesia
Anterior Chamber
Busan
Cataract
Endothelial Cells
Endothelium
Endothelium, Corneal
Humans
Lidocaine*
Phacoemulsification*
Prospective Studies
Vitrectomy
Lidocaine
Full Text Links
  • JKOS
Actions
Cited
CITED
export Copy
Close
Share
  • Twitter
  • Facebook
Similar articles
Copyright © 2024 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr