J Korean Ophthalmol Soc.  2001 Aug;42(8):1164-1171.

Angiographic Findings of Choroidal Lesions in Serous Retinal Detachment

• Kim IT
• Park SM
• Jun BY

Abstract

PURPOSE: To study the relationship between the damage of retinal pigment epithelum and the lesion of choroidal vessels in various types of the serous retinal detachment(SRD) on fluorescein angiography(FAG) and indocyanine green angiography(ICGA).
METHODS
FAG and ICGA were performed 81 eyes with various types of serous retinal detachment. The series comprised central serous chorioretinopathy(CSC, 63 eyes), toxemia of pregnancy(8 eyes), and Harada's disease(10 eyes).
RESULTS
All the eyes showed dye leakage through the retinal pigment epithelium(RPE) by FAG. Of sixty-three eyes with CSC, sixty eyes showed choroidal tissue staining in late phase on ICGA. Delayed filling of ICG dye in early phase was present around the site of leakage on FAG in 48 eyes with CSC. In toxemia of pregnancy and Harada's disease, all the cases showed delayed choroidal circulation and leakage from choroidal vessels on ICGA. As a common feature, ICGA showed choroidal hypoperfusion or delayed choroidal circulation and choroidal vascular hyperpermeability in the three types of SRD.
CONCLUSIONS
The authors presume that they might contribute to the damage of RPE. The pathogenesis of SRD may be related to the hypothesis fact that choroidal vascular hyperpermeability probably moves fluid into the subretinal space from the choroid.

Keyword

Central serous chorioretinopathy; Choroidal hypoperfusion; Choroidal vascular hyperper-meability; Harada's disease; Toxemia of pregnancy

MeSH Terms

Central Serous Chorioretinopathy
Choroid*
Fluorescein
Indocyanine Green
Pre-Eclampsia
Retinal Detachment*
Retinaldehyde*
Toxemia
Fluorescein
Indocyanine Green
Retinaldehyde