J Korean Ophthalmol Soc.  1995 Jul;36(7):1244-1248.

Spontaneous Resolution of Mitomycin C Trabeculectomy Associated Hypotony Maculopathy

• Lee SM
• Uhm KB

Abstract

Prolonged hypotony and related complications can occur after trabeculectomy, especially with adjunctive mitomycin C. Prolonged hypotony can produce a permanent reduction in vision. A 22-year-old woman with primary open-angle glaucoma underwent uncomplicated trabeculectomy. A sponge soaked with a 0.5mg/ml solution of mitomycin C was placed between the conjunctiva and the scleral flap for 5 minutes. Two weeks after surgery, visual acuity was reduced to 20/400 and intraocular pressure was 3mmHg. There were disc edema, vascular tortuosity, and radiating chorioretinal folds in the macular area. The bleb was pale, highly elevated, and extended for 270 degrees of the limbus. The anterior chamber was formed, and no bleb leak, cyclodialysis cleft, choroidal detachment were seen. Her intraocular pressure was 2-7mmHg during the 12 weeks after surgery. At the last examination, visual acuity improved at the preoperative level of 20/30 and intraocular pressure was 10mmHg. Fortunately, hypotony maculopathy had improved without any specific management.

Keyword

Hypotony maculopathy; Mitomycin C; Trabeclectomy

MeSH Terms

Anterior Chamber
Blister
Choroid
Conjunctiva
Edema
Female
Glaucoma, Open-Angle
Humans
Intraocular Pressure
Mitomycin*
Porifera
Trabeculectomy*
Visual Acuity
Young Adult
Mitomycin