The Chantres of ERG b-wave and Oscillatory Potential in White Rat during Dark Adaptation

Sohn, Byoung Woo; Kim, Jung Woo; Kim, Jae Myung

Abstract

We studied changes of b-wave and oscillatory potential in ERG test during dark adaptation in white rats for the purpose of using it in experimental disease-group and studying difference in man. For this we performed ERG test on normal 14 S-D (Sprague-Dawley) rats (28 eyes) during dark adaptation. The implicit time of a-wave and b-wave was shortend during dark adaptation. The b-wave and oscillatory potential rapidly increased by 20 and 30 minutes during dark adaptation: in b-wave, these values were 425.89 +/- 141.15 micro v, 473.65 +/- 130.35 micro v respectively, and in oscillatory potential, 110.56 +/- 54.82 micro v, 126.27 +/- 48.24 micro v respectively. After then, these were slightly increased. This results reveal that dark adaptatin in ERG test using rats needs sufficient time from 20 minutes to 30 minutes in similar to man. The oscillatory potential in white rat had three components with 1] light stimulus and the increase of amplitude of oscillatory potential was similar to that of b-wave during dark adaptation. But we should consider that the decreased cone function of white rat was different from that of man, that amplitude of b-wave was continously increased without the break point of early 6 minutes, and that the implicit time of b-wave was continously decreased after 10 minute during dark adaptation, when we use rat.