J Korean Ophthalmol Soc.  1993 Nov;34(11):1073-1078.

Dapiprazole for the Reversal of Mydriasis

• Tae JS
• Oh JH

Abstract

Some patients are very sensitive to glare after diagnostic mydriasis with tropicarnide or phenylephrine. It would be desirable to reverse the effects of mydriasis rapidly and safely after diagnostic mydriasis. We assessed the effect of topical dapiprazole, an alpha adrenergic receptor blocker, in reversing mydriasis in 40 dark brown Iris subjects who received tropicamide 1% or phenylephrine 2.5%. There was a significant difference in the decrease in pupil size between the eyes that received dapiprazole and the control eyes. This study suggests that dapiprazole 0.5% eye drops are effective and safe in reversing mydriasis after instilation of tropicamide 1% or phenylephrine 2.5% into dark brown irides.

Keyword

Dapiprazole; Mydriasis

MeSH Terms

Glare
Humans
Iris
Mydriasis*
Ophthalmic Solutions
Phenylephrine
Pupil
Receptors, Adrenergic
Tropicamide
Ophthalmic Solutions
Phenylephrine
Receptors, Adrenergic
Tropicamide