J Korean Ophthalmol Soc.  1975 Mar;16(1):32-35.

Filtering Operation Using Silicone Implant

• Chang BL

Abstract

Filtering operation using silicone implant was performed on 20 Albino Rabbits' eyes. Square-shaped silicone pieces were used as implant in this experiment to prevent adhesion between subconjunctival tissue and sclera. During the experimental course, intraocular pressure, subconjunctival bleb, existance of silicone piece and of scleral gap and state of conjunctiva over the silicone piece were observed and at the end of the experimeit, histopathologic examination was performed. Conjunctival tear was observed over one half of eyes experimented and subconjunctival bleb was not present at all in all cases. The lowering of the intraocular pressure after operation was not significant. Scleral gap was occluded completely or partially by fibrosis and inflammatory cells except 2 eyes. After 5-6 weeks' observation, silicone pieces were remained on position in 5 eyes out of 6. Histopathologically, I observed fibrosis, chronic inflammatory cells and occasionally granulomo atous change of foreign body type near the silicone piece.

MeSH Terms

Blister
Conjunctiva
Fibrosis
Foreign Bodies
Intraocular Pressure
Sclera
Silicones*
Silicones