J Korean Soc Plast Reconstr Surg.  2009 Jul;36(4):493-496.

A Case of Disseminated Multiple Glomus Tumors

Affiliations
  • 1Department of Plastic and Reconstructive Surgery, Seoul National University College of Medicine, Seoul, Korea.
  • 2Department of Plastic and Reconstructive Surgery, Keimyung University School of Medicine, Daegu, Korea. handson@dsmc. or.kr
  • 3Department of General Surgery, Keimyung University School of Medicine, Daegu, Korea.

Abstract

PURPOSE
Glomus tumors are neoplasms that are composed of modified smooth muscle cells of the glomus body and multiple glomus tumor comprises 10% of all glomus tumors. We report a case of disseminated multiple glomus tumors.
METHODS
A 14-year-old boy presented with multiple subcutaneous purple nodules on the right cheek, back, right arm, right hand dorsum, right fourth finger, and left ankle. Nodules on the back and right fourth finger were completely excised under local anesthesia and histopathologic examination was followed.
RESULTS
Histopathologic findings showed numerous dilated, cavernous-like, thin-walled vascular spaces surrounded by one or a few layers of glomus cells. On immunohistochemical examination, glomus cells stain for smooth muscle actin, and endothelial cells stain for CD31. Those revealed multiple glomangiomas.
CONCLUSION
A review of Korean literature revealed only one reported case of disseminated multiple glomus tumors, so this is the second case to be reported in the Korean literature. In case of multiple soft tissue tumors, thorough physical examination and preoperative evaluation are needed.

Keyword

Disseminated multiple glomus tumors; Glomangioma

MeSH Terms

Actins
Adolescent
Anesthesia, Local
Animals
Ankle
Arm
Cheek
Endothelial Cells
Fingers
Glomus Tumor
Hand
Humans
Muscle, Smooth
Myocytes, Smooth Muscle
Physical Examination
Actins
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