Korean J Dermatol.  1998 Jun;36(3):536-539.

A Case of Gloves and Socks Syndrome

• Jeong HH
• Jang JG
• Chae YS
• Suh KS
• Kim ST

Abstract

Clinical characteristics of papular-purpuric gloves and socks syndrome consist of a purpuric erythema affecting the hands and feet in a gloves and stocking distribution. It is sometimes associated with fever and oral lesions. The disease is self-limiting and resolves within 1 to 2 weeks. Serological studies have shown that there is an association with parvovirus B19 infection in most patients affected by this syndrome. We report a case of gloves and socks syndrome in a 21-year-old female. She had a 4-day history of papular-purpuric eruptions of the hands and feet in a gloves-and-socks distribution. She also complained of fever(up to 39C) during the first 2 or 3 days of clinical onset. The oral mucosa was normal and there were no palpable lymph nodes. Laboratory and histopathological findings were non-specific. However, human parvovirus B19 DNA was detected in the serum by a polymerase chain reaction. Systemic manifestations were transient and disappeared within a few days, whereas the skin lesions resolved gradually over a period of 2 weeks.

MeSH Terms

DNA
Erythema
Female
Fever
Foot
Hand
Humans
Lymph Nodes
Mouth Mucosa
Parvovirus
Parvovirus B19, Human
Polymerase Chain Reaction
Skin
Young Adult
DNA