Korean J Dermatol.
1998 Jun;36(3):407-414.
Clinical Effects of Photodynamic Therapy on Carcinoma In Situ of the Skin
Abstract
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BACKGROUND: Photodynamic therapy(PDT) is a type of photochemotherapy that is designed to kill targeted tumor cells.
OBJECTIVE
The Clinical effects of PDT were analysed for response rates, post-treatment healing and adverse effects on several cutaneous carcinoma in situ.
METHOD: PDT with topical 5-aminolevulinic acid-based irradiation of corresponding 630+5nm light was performed in 6 carcinoma in situ patients who had actinic keratosis, Bowen' disease or cutaneous squamous cell carcinoma.
RESULT: In all patients the clinical results were exellent with respect to initial complete responses and cosmetic outcome.
CONCLUSION
PDT might be chosen as a first line treament for cutaneous carcimoma in situ.