Tuberc Respir Dis.  2015 Jan;78(1):23-26. 10.4046/trd.2015.78.1.23.

Indolent Metastatic Squamous Cell Carcinoma of Unknown Primary in the Intrathoracic Lymph Node: A Case Report and Review of the Literatures

• Kim MJ
• Lim SH
• Han SJ
• Choi KH
• Lee SH
• Park MW
• Kang H
• Na JO

• KMID: 2114645
• DOI: http://doi.org/10.4046/trd.2015.78.1.23

Abstract

Metastatic squamous cell carcinoma from a cancer of unknown primary (CUP) affecting the intrathoracic lymph node is very rare. We reported a case of metastatic squamous cell carcinoma in the hilar and interlobar lymph node from a patient with CUP and reviewed the associated literature. Abnormal mass in the right hilar area was incidentally detected. A chest computed tomography scan showed a 2.5-cm diameter mass in the right hilum that had changed little in size for 3 years. The patient underwent a right pneumonectomy and mediastinal lymph node dissection. A metastatic squamous cell carcinoma in the hilar and interlobar lymph nodes without a primary lung or other lesion was diagnosed. The patient received adjuvant chemotherapy for a diagnosis of T0N1M0 lung cancer.

Keyword

Neoplams; Unknown Primary; Carcinoma; Squamous Cell

MeSH Terms

Carcinoma, Squamous Cell*
Chemotherapy, Adjuvant
Diagnosis
Humans
Lung
Lung Neoplasms
Lymph Node Excision
Lymph Nodes*
Pneumonectomy
Thorax

Figure

• 

  Figure 1 Chest computed tomography (CT) scan in December of 2012 (B) showed a 2.5-cm diameter hilar mass that was little changed, as compared to the cardiac angio CT scan in March of 2010 (A).

• 

  Figure 2 Grossly, several enlarged lymph nodes (arrows) were found in the hilar and interlobar area.

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  Figure 3 Microscopic finding showed metastatic squamous cell carcinoma to the lymph nodes (H&E stain, ×40; insert image: H&E stain, ×200).

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