J Korean Ophthalmol Soc.  2002 Apr;43(4):786-790.

Gonococcal Keratoconjunctivitis in Adult

Affiliations
  • 1Department of Ophthalmology, College of Medicine, Pusan National University, Pusan, Korea. jongsool@hyowon.pusan.ac.kr
  • 2Mirae Eye Center, Korea.

Abstract

PURPOSE: Neisseria gonorrhea is usually identified in neonatal conjunctivitis, but rare in adult keratoconjunctivitis. We report a rare case of bilateral gonococcal conjunctivitis combined with keratitis.
METHODS
A 29-year-old male with a history of sexual contact with a prostitute 17 days ago referred to our hospital with acute keratoconjunctivitis. Ocular discharge was examined by Gram stain, culture, and sensitivity test to antibiotics, resulting in the identification of penicillin-resistant Neisseria gonorrhea.
RESULTS
This patient was treated with intramuscular ceftriaxone for 5 days and topical cefmenoxime 0.5% for 2 weeks. Following 24 hours after antibiotics medication, the clinical symptoms were improved, and follow-up culture was negative. No evidence of serious complication was left in the cornea and conjunctiva.
CONCLUSIONS
As adult gonococcal keratoconjuctivitis is relatively rare, the clinical diagnosis may be delayed. When one suspects an adult gonococcal keratoconjunctivitis, immediate gram staining and confirmatory culture for isolation of gram-negative intracellular diplococci are mandatory. It should be remembered that intramuscular ceftriaxone and topical cefmenoxime are an effective treatment for this condition.

Keyword

Cefmenoxime (Bestron R ); Ceftriaxone (Rocephin R ); Gonococcal keratoconjunctivitis; Penicillin-resistant Neisseria gonorrhea

MeSH Terms

Adult*
Anti-Bacterial Agents
Cefmenoxime
Ceftriaxone
Conjunctiva
Conjunctivitis
Cornea
Diagnosis
Follow-Up Studies
Gonorrhea
Humans
Keratitis
Keratoconjunctivitis*
Male
Neisseria
Sex Workers
Anti-Bacterial Agents
Cefmenoxime
Ceftriaxone
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