J Korean Ophthalmol Soc.  2001 Sep;42(9):1367-1370.

Intravenous Thrombus Formation in Branch Retina Vein Occlusion

• Kim IT
• Jung BY
• Na SC

Abstract

PURPOSE: It is very rare to observe the thrombus formation next to the ateriovenous crossing(AV crossing) in branch retinal vein occlusion(BRVO). We investigated two cases with the thrombus in BRVO.
MATERIALS AND METHODS
Two of 347 cases with BRVO to perform the fluorescein angiography(FAG) were observed to form the intravascular thrombus next to the AV crossing.
RESULTS
The vascular wall in the area of thrombus was hyperfluorescent in FAG. The fluorescence was visible in the early arteriovenous phase and it increased in the mid-phase of the angiogram. Investigatons for systemic hypertension and hyperlipidemia in two cases were positive. The vascular wall in the area of thrombus in one case revealed as hyperfluorescence exaggeratedly in length by forward and backward movement of the thrombus during performing FAG. And the leakage of fluorescein from the venule next to the AV crossing was not observed. In the other case, the vascular wall in the area of thrombus revealed the small hyperfluorescent spot and the leakage of fluorescein.
CONCLUSIONS
The pathogenesis of thrombus formation in the retinal vein resulting in retinal vein occlusion is not well understood. Although poststenotic turbulence of blood flow after an AV crossing or a preexisting vessel wall alteration combined with alterations of blood fluidity may induce thrombus formation, it was uncertain in our cases whether or not the thrombus formation was associated with hyperlipidemia, systemic hypertension, and hypercoaguable states.

Keyword

Retinal branch vein occlusion; Thrombus

MeSH Terms

Fluorescein
Fluorescence
Hyperlipidemias
Hypertension
Retina*
Retinal Vein
Retinal Vein Occlusion
Thrombosis*
Veins*
Venules
Fluorescein