J Korean Ophthalmol Soc.  1987 Dec;28(6):1285-1288.

Clinical Effects of Topical Betaxolol Hydrochloride(Betoptic(R)) in Glaucoma Patients

• Hong C
• Song KY
• Youn DH

Abstract

To evaluate the clinical usefulness of a newly developed beta-one selective blocker. Betaxolol hydrochloride(Betoptice(R)), seven patients(14 eyes) with primary open-angle glaucoma who were instilled twice a day with a drop of 0.5% Betoptic were enrolled in this study. Intraocular pressure(IOP), systolic and diastolic blood pressure, pulse rate and pupil size were measured with the evaluation on the local adverse reaction before and after the Betoptic treatment of 1, 2, 4, 8 and 12 weeks. The following results were obtained: 1. Significant reduction of IOP was noted at all intervals examined after the treatment of 0.5% Betoptic and it had the additive effect on pilocarpine. 2. The systemic side reaction of Betoptic on either pulse rate or blood pressure was not significant and pupil size was not changed by Betoptic. 3. The local transient and mild stinging sensation with tearing was followed after the instillation of 0.5% Betoptic eye solution.

MeSH Terms

Betaxolol*
Bites and Stings
Blood Pressure
Glaucoma*
Glaucoma, Open-Angle
Heart Rate
Humans
Pilocarpine
Pupil
Sensation
Betaxolol
Pilocarpine