J Korean Ophthalmol Soc.
1979 Dec;20(4):445-449.
Characteristics of fine Structures in the Experimental Retinal Dysplasia of Rats and Retinoblastoma: An electron microscopic study
- Affiliations
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- 1Department of Ophthalmology, Paik Hospital, Seoul, Inje Med ical College, Korea.
- 2Department of Ophthalmology, College of Medicine, Chung Ang University, Korea.
Abstract
- Retinal dysplasia is an important disease in the study of retinal development. The differential diagnosis of retinal dysplasia from retinoblastoma is very difficult to make clinically, but histologically the diagnosis is made by the structure of rosettes. The authors experimentally gave trauma to retina of rats and produced retinal dysplasia; we observed under electron microscope the incomplete rosette of retinal dysplasia and the complete rosette appearing in retinoblastoma. We concluded that both rosettes are formed in developing retina with environmental or hereditary defects and did a comparative study of their characteristic fine structures.
