J Korean Pain Soc.
1998 May;11(1):74-80.
Pain Control after Dental Surgery: Myprodol Versus Ibuprofen Versus Codeine
Abstract
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BACKGROUND: Myprodol, a newly introduced combination analgesics with codeine, ibuprofen and paracetamol was evaluated in the dental surgery patients for its efficacy and side effects.
METHODS
Total 60 ASA I or II outpatients dental surgical patients were randomly assigned into three groups(n 20 each). After various oral procedures, one of three oral analgesics, myprodol, ibuprofen or codeine, was prescribed to each patients in double blind fashion for three days. Each patient was followed carefully by daily phone calls for verbal analog pain scale, side effects and patient's satisfaction level.
RESULTS
Demographic data and duration of surgery revealed no statistical differences in all three groups. Myprodol group showed better verbal analgesic scores consistently for the study period than ibuprofen or codeine group. Adverse effects were minimal. Patients' satisfaction level was high in all three groups.
CONCLUSION
We conclude that myprodol is an excellent oral analgesic for day-surgery based dental procedure patients. This effect appears to be synergistic among different analgesics rather than additive.