J Korean Pediatr Soc.
1998 Oct;41(10):1424-1439.
A Case of Congenital Self-Healing Reticulohistiocytosis
- Affiliations
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- 1Department of Pediatrics, Sung-Ae General Hospital, Seoul, Korea.
- 2Department of Pathology, Sung-Ae General Hospital, Seoul, Korea.
- 3Department of Pathology, School of Medicine, Chung-Ang University, Seoul, Korea.
Abstract
- Congenital self-healing reticulohistiocytosis (CSHR) is a rare variant of cutaneous reticulohistiocytosis. We report a newborn who had about 25 reddish brown papulonodular lesions on whole body at birth. No extracutaneous involvement was found. All skin lesions involuted within 4 months spontaneously. Biopsy of a skin lesion showed marked aggregated histiocytic infiltration with some eosinophils. S-100 protein and lysozyme were positive. Electron microscopy revealed numerous dense bodies, often with a myelin-like core and some Birbeck granules. We described a detailed clinical features of this case and reviewed the literatures.
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