J Korean Pediatr Soc.  1980 Sep;23(9):710-716.

Clinical Review of Diabetes Insipidus in Children

• Lee CM
• Chung YH

Abstract

Clinical review of 5 pediatric diabetes insipidus, who have been admitted and treated at Dept. of Pediatric in Chungnam University Hospital from Aug. 1974 to May 1979, were summarized as follows: 1) The common complaints were polyuria and polydipsia, and anorexia, general weakness, poor visual acuity, vomiting, and headache were associated occasionally. 2) Male to female ratio was 3:2, the age distribution was between 4 to 13 years old. 3) The duration which was from onset to visiting hospital was betwen 5 months to 13 months. 4) Etiologic causes were 2 cases of idiopathic, 1 of pinealoma, 1 of head trauma, and 1 of nephrogenic origin.5) Urine specific gravity was below 1.004 in all cases, and the amount of urine output per day was 4.8l to 5.9l. 6) Hypernatremia was observed in nephrogenic case but others were within normal limits. 7) On simple skull X-ray, calcification was seen in pinealoma which was displaced upward and backed, and it was confirmed by C-T scan. 8) Chlorpropamide was effective on idiopathic and traumatic origin but there was no response on nephrogenic origin.

MeSH Terms

Adolescent
Age Distribution
Anorexia
Child*
Chlorpropamide
Chungcheongnam-do
Craniocerebral Trauma
Diabetes Insipidus*
Female
Headache
Humans
Hypernatremia
Male
Pinealoma
Polydipsia
Polyuria
Skull
Specific Gravity
Visual Acuity
Vomiting
Chlorpropamide