J Korean Radiol Soc.  2007 Apr;56(4):315-320. 10.3348/jkrs.2007.56.4.315.

The Safety and Efficacy of Hemostasis with Clo-Sur P.A.D. after Transcatheter Arterial Chemoembolization

• Jung SC
• Jae HJ
• Kim SY
• Lee W
• Chung JW
• Park JH

• KMID: 2103853
• DOI: http://doi.org/10.3348/jkrs.2007.56.4.315

Abstract

PURPOSE
We wanted to evaluate the safety and efficacy of a new hemostatic device, Clo-Sur P.A.D., at an arterial access site after performing femoral arterial catheterization to achieve transcatheter arterial chemoembolization (TACE).
MATERIALS AND METHODS
From August 2002 to March 2005, 113 patients who underwent TACE and agreed on using the Clo-Sur P.A.D. were enrolled in this study. We evaluated the mean time interval from compression to the first movement and also to the first walk. We also evaluated such complications as rebleeding, pseudoaneurysm, vascular occlusion, hematoma, infection and pain. For 92 patients who had previous experiences with manual compression, we evaluated their preference of hemostatic method by asking them.
RESULTS
Successful hemostasis was achieved with the Clo-Sur P.A.D. in 105 subjects (92%). The mean time interval from compression to the first movement was 201 minutes, and that to the first walk was 267 minutes. There was no statistical difference between the complicated and the uncomplicated groups for the mean time, prothrombin time, Child-Pugh class and platelet count (p > 0.05). Rebleeding occurred in 3 patients (2.7%) and mild hematoma around puncture site was noted in 5 patients (5.4%). Eighty-seven patients (95%) preferred Clo-Sur P.A.D. to the manual compression method.
CONCLUSION
The Clo-Sur P.A.D. is a safe and effective hemostatic device and it provides early ambulation after TACE.

Keyword

Arteries, femoral; Arteries, interventional procedures; Catheters and catheterization, complications; Hepatic arteries, chemotherapeutic embolization

MeSH Terms

Aneurysm, False
Catheterization
Catheters
Early Ambulation
Femoral Artery
Hematoma
Hemostasis*
Humans
Platelet Count
Prothrombin Time
Punctures