J Korean Radiol Soc.  2006 Dec;55(6):579-589. 10.3348/jkrs.2006.55.6.579.

Imaging Findings of Abdominal Extraosseous Plasma Cell Neoplasm

Affiliations
  • 1Department of Radiology and Research Institute of Radiology, University of Ulsan College of Medicine, Asan Medical Center, Korea. jhbyun@amc.seoul.kr
  • 2Department of Diagnostic Radiology, Gyeongsang National University College of Medicine, Korea.

Abstract

PURPOSE
To evaluate the imaging findings of abdominal extraosseous plasma cell neoplasm.
MATERIALS AND METHODS
From April 2000 to January 2005, eight patients (four men, four women; mean age, 50.6 years) with pathologically proved, extraosseous plasma cell neoplasm involving the abdominal organs were included in this study. The diagnoses were based on consensus agreement between two radiologists who retrospectively reviewed CT, ultrasonography, and enteroclysis findings. We evaluated the findings by focusing on the location, size, margin, and enhancement pattern of the lesion, and lymphadenopathy on each image.
RESULTS
There were multiple myeloma in four patients and extramedullary plasmacytoma in the remaining four. Involved abdominal organs were the liver (n = 4), spleen (n = 4), lymph node (n = 3), stomach (n = 1), small bowel (n = 1), and colon (n = 1). The hepatic involvement of plasma cell neoplasm presented as a homogeneous, well-defined, solitary mass (n = 1), multiple nodules (n = 1), and hepatomegaly (n = 2). Its involvement of the spleen and lymph node appeared as splenomegaly and lymphadenopathy, respectively. Its involvement of the gastrointestinal tract including the stomach, small bowel, and colon, presented as a homogeneous, diffuse wall thickening or mass in the gastrointestinal tract.
CONCLUSION
Abdominal extraosseous plasma cell neoplasm involves occasionally the liver, spleen, and lymph node, and rarely the gastrointestinal tract. When we encounter a well-defined, homogeneous lesion of the abdominal organs in patients diagnosed or suspected as having plasma cell neoplasm, we should consider its involvement of the abdominal organs.

Keyword

Computed tomography (CT); Ultrasound (US); Liver; Stomach; Plasmacytoma

MeSH Terms

Colon
Consensus
Diagnosis
Female
Gastrointestinal Tract
Hepatomegaly
Humans
Liver
Lymph Nodes
Lymphatic Diseases
Male
Multiple Myeloma
Neoplasms, Plasma Cell*
Plasma Cells*
Plasma*
Plasmacytoma
Retrospective Studies
Spleen
Splenomegaly
Stomach
Ultrasonography
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