J Korean Radiol Soc.
1994 Jan;30(1):187-192.
Neuroblastoma: Computed Tomographic Findings
Abstract
- PURPOSE: To evaluate the characteristic CT findings of neuroblastoma, we studied neurobalstomas.
METHODS
AND MATERIALS: We analysed CT findings of available 25 cases among pathologically proved 51
neurobalstomas from Jan. 1983 to Sept. 1990.
RESULTS
The most frequent site of origin is adrenl gland (40%) and the second is retroperitoneum (32%) and
the third ismediastinum (16%). Characteristic CT findings are as follows:Calcifications within the tumor is
detected in 86% of abdominal neuroblastomas and 50% of mediastinal origin. Hemorrhagic and necrotic
changes within the tumor is noted at 86% in the tumor of abdominal origin and 25% in mediastinal
neuroblastomas. Contrast enhanced study showed frequently septated enhanced appearance with/without solid
contrast enhancement. Encasements of major great vessels such as aorta and IVC with/without displacement
by metastatic lymphnodes or tumor are frequently seen in 90% of abdominal neuroblastomas. Multiple
lymphadenopathy are detected in 95% of abdominal neurobalstomas and 25% of mediastinal neuroblastomas.
The most common organ of contiguous direct invasion is kidney in 6 cases and the next one is liver but
intraspinal canal invasion is also noted in 2 cases.
CONCLUSION
We concluded that diagnosis of neuroblastoma would be easily obtained in masses of pediatric
group from recognition of above characteristic findings.