J Korean Soc Clin Toxicol.  2011 Dec;9(2):113-116.

A Case of Prolonged Coagulopathy in a Patient Intoxicated with Superwarfarin Rodenticide

Affiliations
  • 1Department of Emergency Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University, Korea. cjhemd@kangwon.ac.kr
  • 2Department of Internal Medicine, School of Medicine, Kangwon National University Hospital, Kangwon National University, Korea.

Abstract

Superwarfarin, such as brodifacoum, is a highly lethal vitamin K antagonist used as a rodenticide. Brodifacoum has a particularly long half-life in the body, which ranges to several months, and therefore requires prolonged treatment with antidotal vitamin K. We experienced a case whereby an 18-year-old male was presented to the hospital with a severe bleeding disorder. It was discovered that he had ingested brodifacoum rodenticide with intent to commit suicide. Despite continual treatment with vitamin K, the bleeding disorder persisted for several months before he recovered. We report this case with literature review.

Keyword

Anticoagulant; Coagulopathy; Poisoning; Rodenticide; Vitamin K

MeSH Terms

4-Hydroxycoumarins
Adolescent
Half-Life
Hemorrhage
Humans
Male
Suicide
Vitamin K
Vitamins
4-Hydroxycoumarins
Vitamin K
Vitamins
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