J Korean Soc Radiol.  2011 Mar;64(3):249-252. 10.3348/jksr.2011.64.3.249.

MR Imaging Features of Primary Cutaneous Diffuse Large B-cell Lymphoma: A Case Report

• Park JI
• Kim JW

• KMID: 2097946
• DOI: http://doi.org/10.3348/jksr.2011.64.3.249

Abstract

Here we report magnetic resonance (MR) imaging findings for a case of primary cutaneous diffuse large B-cell lymphoma (PCDLBCL) located in the chest wall, a rare type of lymphoma, occurring in a 67-year-old woman. Although rare, PCDLBCL may be one of the diagnostic inclusions for a soft tissue mass in the subcutaneous layer of the trunk, especially when the mass shows hyperintensity in relation to the muscle on T2-weighted MR images and peripheral enhancement on contrast enhanced T1-weighted MR images.

MeSH Terms

Aged
B-Lymphocytes
Epidermal Cyst
Female
Humans
Lymphoma
Lymphoma, B-Cell
Lymphoma, Large B-Cell, Diffuse
Magnetic Resonance Imaging
Magnetic Resonance Spectroscopy
Muscles
Soft Tissue Neoplasms
Thoracic Wall

Figure

• 

  Fig. 1 67-year-old woman with painful primary cutaneous diffuse large B-cell lymphoma in the left posterior chest wall. A. This Axial T1-weighted image shows a hypointense lesion and a peripheral high signal intensity rim on the chest wall. B. An axial T2-weighted image showing a lobulating subcutaneous mass with a central high signal intensity and peripheral low signal intensity rim. C. A gadolinium-enhanced, fat-suppressed, T1-weighted image that shows a mass with thick and irregular peripheral enhancement. Subtle subcutaneous and overlying skin enhancements (arrow) are present near the mass. D. Photomicrography of the skin shows diffuse dermal infiltration by large atypical lymphocytes (H & E stain, ×40). E. Immunohistochemical staining of tumor cells showing expression of CD20.

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