Korean Circ J.  1988 Jun;18(2):251-255. 10.4070/kcj.1988.18.2.251.

Clinical Trial on the Antianginal Effect of Trapidil

• Son JH
• Shim JG
• Kim JH
• Lim HK
• Lee BH
• Lee CK

• KMID: 2093237
• DOI: http://doi.org/10.4070/kcj.1988.18.2.251

Abstract

Antianginal effect of Trapidil was evaluated in 30 patients (18 male and 12 females) with angina rectoris. The results were follows : 1) Antianginal effect of the drug were good in 18 cases (60%) and fair in 8 cases (37%), and there was no effect in 4 cases(13%). 2) Improvement in ECG changes was observed in 29%. 3) There were no significant change in CBC, RUA, LFT, serum electrolyte and lipid study before and after medication. 4) The adverse effects of trapidil were constipation, gastric cramp and dizziness, respectively one case. But they were not required discontinuing the medicetion. On the basis of these results, Trapidol was evaluated to be promising antianginal drug.

MeSH Terms

Constipation
Dizziness
Electrocardiography
Humans
Male
Muscle Cramp
Trapidil*
Trapidil