Korean J Anesthesiol.  2011 Nov;61(5):394-398. 10.4097/kjae.2011.61.5.394.

A comparison of the influence of 2.7% sorbitol-0.54% mannitol and 5% glucose irrigating fluids on plasma serum physiology during hysteroscopic procedures

• Park JT
• Lim HK
• Kim SG
• Um DJ

• KMID: 2092321
• DOI: http://doi.org/10.4097/kjae.2011.61.5.394

Abstract

BACKGROUND
2.7% sorbitol-0.54% mannitol has been selected as an alternative irrigating fluid during endoscopic surgery for its theoretical advantages. We compared the influence of 2.7% sorbitol-0.54% mannitol (Urosol(TM), CJ Pharma, Seoul, Korea) and 5% glucose as an irrigating solution for hysteroscopic myomectomy & polypectomy in the occurrence of associated complications.
METHODS
Thirty patients scheduled for a hysteroscopic operation were included in a prospective randomized trial comparing 2.7% sorbitol-0.54% mannitol solution (Group S, n = 15) and 5% glucose (Group G, n = 15) as an irrigating fluid. We recorded the amount of the irrigating fluids, the amount of fluid intake, and the duration of the procedure. Serum sodium, chloride, potassium, glucose values, and serum osmolality were measured before (just after the induction, T1), during (when 2 L of irrigation fluid was infused, T2), and after (1 h after the end of the operation, T3) the hysteroscopic procedure.
RESULTS
The mean volume of absorbed irrigating fluid was 185.0 +/- 73.5 ml in Group G and 175.4 +/- 50.5 ml in Group S. Transient hyperglycemia occurred in one patient of Group G. No differences were found in the intraoperative and postoperative levels of serum sodium, potassium, chloride, glucose and osmolality in both groups.
CONCLUSIONS
There was no clinical evidence of hyponatremic hypoosmolality in any of the patients. We found no difference between 2.7% sorbitol-0.54% mannitol and 5% glucose as an irrigating fluid for hysteroscopic procedures with mild to moderate irrigant absorption.

Keyword

Complication; 5% Glucose solution; Hysteroscopy; Sorbitol-mannitol solution

MeSH Terms

Absorption
Glucose
Humans
Hyperglycemia
Hysteroscopy
Mannitol
Osmolar Concentration
Plasma
Potassium
Potassium Chloride
Prospective Studies
Sodium
Glucose
Mannitol
Potassium
Potassium Chloride
Sodium