Korean J Anesthesiol.  2006 May;50(5):511-514. 10.4097/kjae.2006.50.5.511.

Effect of Nitrous Oxide on Bispectral Index during Sevoflurane Anesthesia

Affiliations
  • 1Department of Anesthesiology and Pain Medicine, College of Medicine, Hanyang University, Seoul, Korea. yeomjh@hanyang.ac.kr

Abstract

BACKGROUND: Nitrous oxide is generally avoided in order to prevent either hypoxia or graft dislodgment during tympanoplasty. The aim of this study was to investigate the effect of nitrous oxide on the bispectral index during sevoflurane anesthesia at the anesthetic dose.
METHODS
The bispectral index was continually measured during nitrous oxide-oxygen-sevoflurane anesthesia, discontinuation of nitrous oxide and the reintroduction of nitrous oxide.
RESULTS
The bispectral index of nitrous oxide-oxygen-sevoflurane anesthesia increased after discontinuing the nitrous oxide and decreased after its reintroduction.
CONCLUSIONS
Nitrous oxide decreased the bispectral index of nitrous oxide-oxygen-sevoflurane anesthesia compared with oxygen-sevoflurane anesthesia at the anesthetic dose.

Keyword

bispectral index; nitrous oxide; sevoflurane

MeSH Terms

Anesthesia*
Anoxia
Nitrous Oxide*
Transplants
Tympanoplasty
Nitrous Oxide
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