Korean J Anesthesiol.  1998 Jun;34(6):1227-1231. 10.4097/kjae.1998.34.6.1227.

Dose Thoracoscopic Sympathectomy for Hyperhidrosis Increase Airway Pressure?

• Shin CS
• Lee HC
• Kim JE
• Kim GS

• KMID: 2091225
• DOI: http://doi.org/10.4097/kjae.1998.34.6.1227

Abstract

BACKGROUND: Bilateral interruption of the upper thoracic sympathetic chain at T2 level represents a selective cure for essential hyperhidrosis. Following the surgical sympathectomy, significant changes in pulmonary function has been observed. Our hypothesis was that thoracic sympathectomy may increase airway resistance during mechanical ventilation and which may be attenuated by the anticholinergics.
METHODS
21 patients with essential hyperhidrosis in ASA physical status class 1 under going thoracoscopic sympathectomy, they were randomizely divided into two groups: glycopyrrolate premedication group (n=13) and non-premedication, control group (n=9). Glycopyrrolate 0.2 mg was administered 30 minutes before the induction of anesthesia. Blood pressure, heart rate, peak airway pressure, plateau pressure were measured at before and immediate after sympathectomy. Respiratory compliance and resistance were calculated.
RESULTS
After thoracoscopic sympathectomy, there was significant increase in mean peak airway pressure (15 +/- 3 vs 18 +/- 3 cmH2O, P<0.05) and decrease in respiratory compliance (52 +/- 12 vs 45 +/- 10 ml/cmH2O, P<0.05) compared to baseline. However there was no significant difference between glycopyrolate premedication group and non-premedication group.
Conclusion
Thoracoscopic upper dorsal sympathectomy in patients with essential hyperhidrosis causes increase peak airway pressure and decrease the compliance of respiratory system during mechanical ventilation.

Keyword

Lung: airway resistance; Premedication: glycopyrrolate; Surgery: thoracoscopic sympathectomy

MeSH Terms

Airway Resistance
Anesthesia
Blood Pressure
Cholinergic Antagonists
Compliance
Glycopyrrolate
Heart Rate
Humans
Hyperhidrosis*
Premedication
Respiration, Artificial
Respiratory System
Sympathectomy*
Cholinergic Antagonists
Glycopyrrolate