Korean J Anesthesiol.  1997 Jan;32(1):91-96. 10.4097/kjae.1997.32.1.91.

The Effect of Lidocaine with Combined Drugs on Onset Time and Duration of Caudal Anesthesia

• Rah EG
• Yang HS

• KMID: 2091048
• DOI: http://doi.org/10.4097/kjae.1997.32.1.91

Abstract

BACKGROUND: caudal anesthesia is a safe and reliable technique for surgical anesthesia as well as an alternative to narcotics for postoperative analgesia for procedure below umbilicus. Onset time and duration of local anesthetics had been influenced by local anesthetics with combined drugs. We wanted that the time required for the onset of local anesthesia should be short and long enough to allow time for the contemplated surgery. METHOD: To investigated the effect of lidocaine with combined drugs, 120 ASA physical status I, II patients who underwent perianal surgery with caudal anethesia. The patients were diveded into 5 groups : control group received 1.5% lidocaine 27ml, group I received lidocaine with epinephrine (1:200,000), group II received lidocaine with morphine 2mg, group III received lidocaine with fentanyl 50 g, group IV received lidocaine with clonidine 75 g. We have compared the onset time and duration of analgesia of 5 groups.
RESULTS
1. The onset time of analgesia for pin prick test were not significantly changes between groups. 2. The duration of analgesia was significantly more prolonged in group II(863.8 222.1 min) than other three group I, III, IV. 3. The most common side effect was urinary retention(20 cases, 16.7%) in all groups(n=120). 6 cases(24%) in group II(n=25), 2 cases(8%) in group III(n=25) were complained of pruritus. Bradycardia and hypotension were observed in group IV(n=20) (each 1 cases, 5%).
CONCLUSIONS
It is suggested from the above results that the morhine group during caudal anesthesia can produce more prolonged duration of analgesia.

Keyword

Anesthetic techniques; caudal; Analgesics; morphine; fentanyl; epinephrine; clonidine; Anesthesia; onset; duration

MeSH Terms

Analgesia
Analgesics
Anesthesia
Anesthesia, Caudal*
Anesthesia, Local
Anesthetics, Local
Bradycardia
Clonidine
Epinephrine
Fentanyl
Humans
Hypotension
Lidocaine*
Morphine
Narcotics
Pruritus
Umbilicus
Analgesics
Anesthetics, Local
Clonidine
Epinephrine
Fentanyl
Lidocaine
Morphine
Narcotics