Korean J Anesthesiol.  1992 Jun;25(3):596-601. 10.4097/kjae.1992.25.3.596.

The Effects of Depolarizing and Nondepolarizing Muscle Relaxants on Postoperative Sore Throat , Hoarseness , and Myalgia

• Woo YC
• Kim HM
• Lim SH
• Park YC
• Lee MK
• Kim NS
• Choi YS

• KMID: 2090721
• DOI: http://doi.org/10.4097/kjae.1992.25.3.596

Abstract

The relationship between different muscle relaxants(vecuronium, pancuronium, succinyl- choline) and postoperative sore throat, hoarseness, and myalgia was evaluated in 46 adult ASA class I women undergoing general anesthesia with endotracheal intubation. All patients were anesthetized with thiopental-N2O-O2 and enflurane. The patients were divided into 3 groups. Patients in group 1(n=15) were given vecuronium, group 2(n= 16) pancuronium, and group 3(n =15) succinylcholine. Patient interviews were conducted at 6~10 hours(h) and 24~30 h postoperatively. Evaluation for severity of sore throat, hoarseness and myalgia was accomplished by scoring according to specific criteria. In groups 1, 2, and 3, 6~10 h postoperatively, the incidence of sore throat was 40%, 50%, and 33%; hoarseness was 40%, 31% and 27%; myalgia was 13%, 6% and 20% respectively. In groups 1, 2, and 3, 24-30 h postoperatively, the incidence of sore throat was 7%, 25%, and 53%; hoarseness was 13%, 31%, and 33%; myalgia was 13%, 19%, and 33% respectively. The use of succinyleholine(Sch) resulted in higher incidence of postoperative sore throat at 24-30 h compared with 6-10 h(p<0.05). These results suggest that administration of SCh may contribute to the occurence of postoperative sore throat.

Keyword

Complications; Hoarseness; Myalgia; Sore throat; Neuromuscular relaxants; Vecuronium; Pancuronium; Succinylcholine

MeSH Terms

Adult
Anesthesia, General
Enflurane
Female
Hoarseness*
Humans
Incidence
Intubation, Intratracheal
Myalgia*
Pancuronium
Pharyngitis*
Succinylcholine
Vecuronium Bromide
Enflurane
Pancuronium
Succinylcholine
Vecuronium Bromide