The Study about the Accuracy of Diacan - S When Had Used to Glucose Oxidase Method and Diascan - S for Blood Glucose

Kim, Seong Jong; Yoo, Hee Koo; Jun, Jong Hun; Shim, Jae Chul; Lee, Dong Ho; Kim, Kyoung Hun; Kim, Kyo Sang; Suh, Jung Kook; Chon, Se Ung; Lee, Hong Sik

Abstract

On department of anesthesiology, Hanyang university hospital, we used to the Diascan-S for portable blood glucose monitoring during surgery with anesthesia. So, we try to know about the accuracy, the precision and the specificity of that instrument. Period to check for blood glucose was devided to 3 groups that are on just after induction, the operation of main lesion, the end of surgery and we compared to the blood glucose level by the Diascan-S and the standard reference test. Central laboratory used glucose oxidase method to check blood glueose as the standard reference test. Thereafter we got the conclusions as follow. 1) We had got to good correlation between the blood glucose level by Diascan-S and the stan-dard reference test. (Y=65+0.64X, correlation coefficiency 0.58, p value; 0.0000) 2) When the blood glucose levels had devided as below from l00 mg/dl, 100 mg/dl to 150 mg/ dl and above 150 mg/dl, we only got to good correlation blood glocose level by Diascan-S and the standard reference test from 100 mg/dl to l50 mg/dl. (Y=11+2.5X, correlation coefficieny ; 0.51, p value ; 0.0000) 3) When we had tested for blood glucose on ]ust after anesthesia induction and the operation on main lesion, the end of surgery, the results of each period have a good correation each other by Diascan-S and the standard reference test. (a) Just after anesthesia induction Y = 51+0.50X, correlation coefficiency 0.52, p value 0.0000 (b) Operation for main lesion Y = 80+0.38X, correlation coefficiency 0.45, p value 0.0000 (c) End of surgery Y = 61+0.54X, correlation coefficiency ; 0.62, p value 0.0000 4) The condition of instrument had devided to two conditions of Diascan-S as was calibrated by technician reqularly or not, got to more confident correlation coefficiency when the Diascan-S had calibrated by technician reqularly. (a) had calibrated reqularly Y = 40+0.62X, correlation coefficiency 0.65, p value: 0.0000 (b) had not calibration Y = 77+0.42X, correlation coefficiency ; 0.36, p value: 0.0026 By above results, we got conclusions that portable glucose monitoring instrument(Diascan-s) can use to know to change of blood sugar during anesthesia. And then, if we got the result of blood glucose level as belows 100 mg/dl or above 150 mg/dl when used Diascan-S, should try to test again and must compared to standard reference test of central laboratory. Diascan-S must be ca)ibrated by technician reqularly if we try to get more accurate results of blood glucose by Diascan-S.