Korean J Anesthesiol.
1990 Aug;23(4):563-567. 10.4097/kjae.1990.23.4.563.
A Study of Changes in Plasma Norepinephrine and Epinephrine to Halothane
- Affiliations
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- 1Department of Anesthesiology, College of Mediciene, Seoul National University, Seoul, Korea.
- KMID: 2090556
- DOI: http://doi.org/10.4097/kjae.1990.23.4.563
Abstract
- The reaction to stress, while vital to the conscious animal, may be detrimental to the surgical patient. To assess the stress-associated action of halothane and its doses, we studied the responses in plasma norepinephrine, epinephrine, blood pressure and heart rate to changes of halothane concentration from 0 MAC to 1.5 MAC in 8 healthy adults. Systolic blood pressure, diastolic blood pressure and mean blood pressure were decreased as the concentration of the halothane increased from 0 MAC 0.5 MAC, 1.0 MAC and 1.5 MAC, respectively. But norepinephrine and epinephrine show no statistic ally significant response to changes in the concentration of halothane.
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