Korean J Blood Transfus.  2014 Dec;25(3):274-282. 10.0000/kjbt.2014.25.3.274.

Factors Affecting the Freshness of Transfused Packed Red Blood Cells

Affiliations
  • 1Department of Laboratory Medicine, Korea University College of Medicine, Seoul, Korea. eqcho1ku@korea.ac.kr

Abstract

BACKGROUND
The relationship between the storage age of packed red blood cells (pRBCs) and clinical outcomes is controversial. However, no systematic study regarding how fresh pRBCs were transfused to patients have been available so far. Therefore, we newly defined concepts for supply age (period from blood collection to supply to hospital), storage age (period from supply to transfusion to patient), and transfusion age (supply age plus storage age) and investigated them. The factors affecting each age were also analyzed.
METHODS
A retrospective analysis for three ages of pRBCs was performed for patients who were transfused > or =1 pRBCs unit at three university hospitals between January 2009 and December 2013. Inventory age (period from blood collection to inventory check point at each blood bank) was prospectively checked on a daily basis for 30 days. Four blood centers and blood groups of transfused pRBCs were included.
RESULTS
The mean supply, storage, and transfusion ages of pRBCs were 6.2, 6.0, and 12.0 days, respectively. 58%, 61%, and 66% of total transfused pRBCs were in a fresh category of supply, storage, and transfusion ages correspondingly. Storage and transfusion ages were affected by ABO blood group, hospitals, and years in listing orders. Inventory age was mainly affected by ABO blood group and hospitals.
CONCLUSION
The freshness of transfused pRBCs was affected by hospitals and blood centers. Therefore, using the supply, storage, transfusion, and inventory ages as new norms can be useful to establishment of inventory and supply policies of hospitals and blood centers.

Keyword

pRBCs; Supply age; Storage age; Transfusion age; Inventory age; Policy

MeSH Terms

Blood Group Antigens
Erythrocytes*
Hospitals, University
Humans
Prospective Studies
Retrospective Studies
Blood Group Antigens
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