Korean J Dermatol.
2013 Jul;51(7):544-547.
Extensive Fasciitis in Sclerotic-type Chronic Cutaneous Graft-versus-Host Disease
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- 1Department of Dermatology, Hanyang University College of Medicine, Seoul, Korea. drko0303@hanyang.ac.kr
Abstract
- Fasciitis can occur very rarely with sclerotic-type chronic cutaneous graft-versus-host disease (GVHD). A 54-year-old woman presented with painful skin tightness on upper and lower limb with limited range of movement. She was diagnosed with chronic myelocytic leukemia 5 years ago and underwent allogeneic bone marrow transplantation. Histopathologically, the interlobular septum of subcutis and fascia were remarkably thickened with fibrosis and moderate inflammatory infiltrates accompanying the dilated lymphatic channels with considerable leakage of lymph fluids. Herein, we report a case of extensive fasciitis as a manifestation of chronic GVHD associated with poor prognosis.
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